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Webinar Information (Free Registration):
Topic: Waking Up to Orexin
Presenter: Emmanuel Mignot, MD, PhD
Format: Interactive and Discussion
Cost: FREE
Date: Tuesday, April 22, 2025
Time: 7:30PM Eastern Time
The Board of Registered Polysomnographic Technologists (BRPT) designates this live educational activity for a maximum of 1.0 Continuing Sleep Technology Education Credits. Individuals should claim only those credits that he/she actually earned in the educational activity.
Closed captioning will be available for this program.
About the Presenter:
Dr. Mignot has worked both as a medical doctor and as a researcher in sleep and neurosciences since moving permanently to the United States in 1989. Most notably, he discovered that human narcolepsy is caused by the autoimmune loss of ~20,000 hypothalamic neurons secreting the wake-promoting peptide hypocretin. He identified HLA-DQB1*06:02 and T-cell receptor genes as major susceptibility genes across ethnic groups, which act together to promote a highly selective T-cell mediated autoimmune process triggered by influenza infection. He has received numerous awards including a Breakthrough Prize and is a member of the National Academies of Sciences and Medicine. He works on many aspects of sleep research and on unravelling the etiologies of various autoimmune diseases affecting the brain. Current studies in his laboratory are expending on these findings and range from clinical/patient oriented (better diagnosis and therapy, epidemiology) to basic (positional cloning, GWAS, proteomics, immunology, physiology, neurosciences, pharmacology) studies in sleep and neurological disorders. In addition to his research, he works with a team of engineers and students, developing at scale machine learning for automatic analysis of thousands of polysomnographic (PSG) “sleep” recordings which is being applied to a sample of 200,000 sleep studies with the goal of using sleep as a predictor of cardiovascular, neurological, and psychiatric diseases. He particularly enjoys working in such a culturally diverse environment as his lab is very international where diversity is celebrated in many ways to instill a sense of belonging for everyone.
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