Oxidative Stress, Inflammation, and Endothelial Dysfunction in Sleep-Related Cardiovascular Disease
Obstructive sleep apnea (OSA) is increasingly recognized as an independent contributor to cardiovascular morbidity through mechanisms involving intermittent hypoxia, oxidative stress, systemic inflammation, and vascular endothelial dysfunction. These interconnected pathways play a central role in the development of hypertension, atherosclerosis, coronary artery disease, heart failure, and stroke.
